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発表論文リスト

北海道情報大学　健康情報科学研究センター 論文リスト　　　2025.3.5現在

  1. Improvement of Cognitive Function by Combining a Food Containing Fermented Rice Bran with Light Exercise – A Randomized, Placebo-controlled, Double-blind, Parallel-group Study – Rikiya Shiwaku, Susumu Yoshino, Takashi Tagawa, Hiroshige Kuwahara, Aiko Tanaka, Hiroyo Kagami-Katsuyama, Naoyuki Honma, Jun Nishihira (2024). Pharmacometrics 107(3/4): 103-117.
  2. Exploring the Relationship Between Dietary Habits and Perceptions of Mental and Physical Disorders, or a Sense of Accomplishment in Japan. Iwasa, T., K. Satoh, M. Hazama, H. Kagami-Katsuyama, N. Ito, M. Maeda-Yamamoto and J. Nishihira (2024). Nutrients 16(21): 3702.
  3. Internal Structure of Dietary Habits as a Restriction on Healthy Eating Policy in Japan. Hazama, M., K. Satoh, M. Maeda-Yamamoto and J. Nishihira (2024). Nutrients 16(14): 2296.
  4. Dietary inflammation, sleep and mental health in the United Kingdom and Japan: A comparative cross‐sectional study . Hepsomali, P., H. Kagami‐Katsuyama, C. Coxon, N. Honma, K. Kinoshita, H. Hattori and J. Nishihira (2024). Nutrition Bulletin 49(3): 396-407.
  5. Effects of Daily Consumption of Scallop Oil Prepared from Internal Organs of Japanese Giant Scallop (Patinopecten yessoensis) on Serum Lipid Composition and Its Safety: A Randomized, Double-blind, Placebo-controlled, Parallel Group Comparison Study. Sugimoto, K., M. Nishimura, N. Ito, R. Hosomi, K. Fukunaga and J. Nishihira (2024). Journal of Oleo Science 73(9): 1201-1212.
  6. Improvement of skin condition and intestinal microbiota via Heyndrickxia coagulans SANK70258 intake: A placebo-controlled, randomized, double-blind, parallel-group comparative study. Togawa, N., R. Yamada, Y. Aoki, S. Suehiro, N. Uchida, A. Haseda, H. Kagami-Katsuyama, N. Honma and J. Nishihira (2024). Nutrition 126: 112533.
  7. Specific Composite Biomarker Profiles for β-Amyloid Accumulation in Peripheral Blood in Healthy Subjects Relevant to Biological Factors: Comparison with Patients with Dementia. Satoh K., Sato-Ueshima M., Kagami-Katsuyama H., Nakamura M., Ogata A., Maeda-Yamamoto M. and Nishihira J., (2024) Journal of Biotechnology and Biomedicine, 7(1), 33.
  8. ヒハツ抽出物含有食品の血管内皮機能に及ぼす影響　ランダム化二重盲検プラセボ対照並行群間比較試験. 窪田俊介, 多田静乃, 水間裕, 勝山(鏡)豊代, 長谷田茜, 本間直幸, 西平順. (2023) 薬理と治療, 51(10): 1593.
  9. Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Tanihiro R., Yuki M., Sasai M., Haseda A., Kagami-Katsuyama H., Hirota T., Honma N. and Nishihira J. (2024). Nutrients, 16(1), 141.
  10. Effect of daily ingestion of Bifidobacterium and dietary fiber on vascular endothelial function: a randomized, double-blind, placebo-controlled, parallel-group comparison study. Azuma, N., Saito, Y., Nishijima, T., Aoki, R., Nishihira, J. (2023). Bioscience, Biotechnology, and Biochemistry, zbad148.
  11. The Relationship between Mental and Physical Minor Health Complaints and the Intake of Dietary Nutrients. Kagami-Katsuyama H, Sato-Ueshima M, Satoh K, Tousen Y, Takimoto H, Maeda-Yamamoto M, Nishihira J. (2023) Nutrients, 15(4), 865.
  12. Dietary supplementation of deoxyribonucleic acid derived from chum salmon milt improves liver function in healthy Japanese individuals: a placebo-controlled, randomised, double-blind, parallel-group clinical trial. Takahashi, Y., Konishi, T., Nishimura, M., and Nishihira, J. (2022). Food & Function, 13(18), 9383.
  13. Evaluation of the efficacy and safety of chum salmon milt deoxyribonucleic acid for improvement of hepatic functions: a placebo-controlled, randomised, double-blind, and parallel-group, pilot clinical trial. Takahashi, Y., Konishi, T., Nishimura, M., and Nishihira, J. (2022). Food & Function, 13(18), 9372.
  14. The Impact of Purple-Flesh Potato (Solanum tuberosum L.) cv.“Shadow Queen” on Minor Health Complaints in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Maeda-Yamamoto M, Honmou O, Sasaki M, Haseda A, Kagami-Katsuyama H, Shoji T, Namioka A, Namioka T, Magota H, Oka S, Kataoka-Sasaki Y, Ukai R, Takemura M, Nishihira J. (2022) Nutrients, 14 (12), 2446.
  15. Effect of quercetin glycosides on cognitive functions and cerebral blood flow: a randomized, double-blind, and placebo-controlled study. Nakamura Y, Watanabe H, Tanaka A, Nishihira J, Murayama N. (2022) European Review for Medical and Pharmacological Sciences, 26(23): 8700-8712.
  16. Continuous partially hydrolyzed guar gum intake reduces cold-like symptoms: a randomized, placebo-controlled, double-blinded trial in healthy adults. Sakai S, Kamada Y, Takano H, Ichikawa M, Kurimoto M, Kagami-Katsuyama, H, Nishihira J, M. Sasaki M. (2022) European Review for Medical and Pharmacological Sciences, 26(14): 5154-5163.
  17. コーヒー由来クロロゲン酸類摂取による食後血中中性脂肪値上昇抑制作用の検討 －プラセボ対照ランダム化二重盲検クロスオーバー試験－. 田中藍子, 勝山(鏡)豊代, 岩井和也, 有木真吾, 森本栞, 西平順. (2021) 薬理と治療, 50(4): 721-731.
  18. 鹿角霊芝の NK 細胞活性化作用の検証のための臨床試験 －プラセボ対照ランダム化二重盲検並行群間比較試験－. 宮崎忠昭, 佐藤孝一, 嶋田貴志, 栗本成敬, 勝山(鏡)豊代. (2021) 薬理と治療, 50(4): 535-550.
  19. 栄養調整ゼリーの継続摂取による疲労感に対する有効性の評価 －プラセボ対照ランダム化二重盲検並行群間比較試験－. 西村三恵, 勝山(鏡)豊代, 西平順. (2021) 薬理と治療, 49(12): 2155-2174.
  20. こんにゃく由来グルコシルセラミド摂取による脳内アミロイドβ蓄積に対する抑制効果の探索的試験 －プラセボ対照ランダム化二重盲検並行群間比較試験－. 江口晃一, 向井克之, 湯山耕平, 栗本成敬, 田中藍子, 勝山(鏡)豊代, 西平順, 門出健次, 五十嵐靖之. (2021) 薬理と治療, 49(8): 1225-1239.
  21. Effect of one-week administration of dipeptidyl peptidase-IV inhibitory peptides from chum salmon milt on postprandial blood glucose level: a randomised, placebo-controlled, double-blind, crossover, pilot clinical trial. Takahashi Y, Kamata A, Nishimura M, Nishihira J.(2021) Food Function. 12(18):8544-8551.
  22. The combined effect of green tea and α-glucosyl hesperidin in preventing obesity: a randomized placebo-controlled clinical trial. Yoshitomi R, Yamamoto M, Kumazoe M, Fujimura Y, Yonekura M, Shimamoto Y, Nakasone A, Kondo S, Hattori H, Haseda A, Nishihira J, Tachibana H.(2021) Scientific Reports. 2021 11(1):19067.
  23. Effect of 12 weeks of continuous burdock sprout extract intake on oxidized LDL: A placebo-controlled, randomized, double-blind, parallel-groups study. Ito N, Ohno A, Yomoda S, Inamasu S, Hattori H, Nishihira J. (2021) Functional Foods in Health and Disease, 11(9), 456-472.
  24. The effect of 24-week continuous intake of quercetin-rich onion on age-related cognitive decline in healthy elderly people: a randomized, double-blind, placebo-controlled, parallel-group comparative clinical trial. Nishihira, J., Nishimura, M., Kurimoto, M., Kagami-Katsuyama, H., Hattori, H., Nakagawa, T., Muro, T., and Kobori, M. (2021). Journal of Clinical Biochemistry and Nutrition, 68(3), 1-13.
  25. Effect of daily intake of heat-killed Lactobacillus plantarum HOKKAIDO on immunocompetence: A randomized, double-blind, placebo-controlled, parallel-group study. Nishihira, J., Haseda, A., Nishimura, M., Sugawara, M., Kudo, M., & Nakagawa, R. (2020). Bioactive Compounds in Health and Disease, 3(3), 32-54.
  26. Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults. Nakamura Y, Watanabe H, Tanaka A, Yasui M, Nishihira J, Murayama N.(2020) Nutrients, 12(4): 1191.
  27. Effects of a Single Intake of Processed Food Containing β-conglycinin-rich Soybeans (Nanahomare) on Postprandial Serum Triglycerides in Healthy Subjects – A Randomized, Double-blinded, Placebo-controlled, Crossover Trial – Nishimura M, Kagami-Katsuyama H, Takahashi Y, Moriyama T, Hajika M, Nishihira J.(2020) 薬理と治療, 48(1): 61-68.
  28. Effect of daily ingestion of quercetin-rich onion powder for 12 weeks on visceral fat: A randomized, double-blind, placebo-controlled, parallel-group study. Nishimura M, Muro T, Kobori M, Nishihira J. (2020) Nutrients, 12(1), 91.
  29. Daily Ingestion of Eggplant Powder Improves Blood Pressure and Psychological State in Stressed Individuals: A Randomized Placebo-Controlled Study. Nishimura M, Suzuki M, Takahashi R, Yamaguchi S, Tsubaki K, Fujita T, Nishihira J, Nakamura K. (2019) Nutrients, 11(11), 2797.
  30. モノグルコシルルチン配合緑茶の12週間継続摂取による内臓脂肪に対する有効性および安全性の評価：プラセボ対照ランダム化二重盲検並行群間比較試験. 西村三恵, 池田大樹, 堀利行, 橋爪雄志, 中西章仁, 西平　順. (2019) 薬理と治療, 47(10)：1631-44.
  31. Amelioration of bowel movement by daily ingestion of Kumaizasa (Sasa. senanensis) powder: A placebo-controlled, randomized, double-blind, parallel-group comparison study. Nishihira J, Hara H, Tanaka A, Kagami-Katsuyama H. (2019) Functional Foods in Health and Disease, 9(5): 341-356.
  32. Effect of 12-Week Daily Intake of the High-Lycopene Tomato (Solanum Lycopersicum), A Variety Named “PR-7”, on Lipid Metabolism: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study. Nishimura M, Tominaga N, Ishikawa-Takano Y, Maeda-Yamamoto M, Nishihira J. (2019) Nutrients, 11(5): 1177.
  33. Effects of daily intake of Harudori-kombu: A randomized,double-blind, placebo-controlled, parallel-group study. Nishimura M, Sugawara M, Kudo M, Kinoshita Y, Yoshino H, Nishihira J. (2019) Functional Foods in Health and Disease, 9(4): 205-223.
  34. Safety and efficacy of adzuki bean extract in subjects with moderate to high LDL-C: a randomized trial. Kitano-Okada T, Nagata R, Han KH, Mikami N, Satoh K, Nishihira J, Sasaki K, Ohba K, Fukusima M. (2019) Biosci Biotechnol Biochem,83(5):933-941.
  35. Effect of Welsh onion (Allium fistulosum) green leaf extract on immune response in healthy subjects: a randomized, double-blind, placebo-controlled study. Hirayama Y, Takanari J, Goto K, Ueda H, Tanaka A, Nishihira J. (2019) Functional Foods in Health and Disease, 9(2): 123-133.
  36. 季節性の目や鼻の不快感に対するフラボノイドおよびロスマリン酸を含有するシソ葉由来食品素材「BenegutTM」の有効性と安全性の評価：健常者を対象とした無作為化プラセボ対照二重盲検並行群間比較試験. 高成 準, 三栖 茉奈美, 前田 哲宏, 福地 有希子, 伊藤 直仁, 西平 順. (2018) 薬理と治療 46(11), 1897-1907.
  37. ルチン高含有ダッタンソバ粉を含むソフトカプセルの継続摂取による血流改善効果：プラセボ対照ランダム化二重盲検並行群間比較試験. 勝山(鏡)豊代, 小山誠一, 佐藤浩二, 西平順.(2018) 薬理と治療, 46(7), 1167 -1176.
  38. Effects of 4-week continuous ingestion of champignon extract on bowel movements and intestinal putrefaction products: A randomized, placebo-controlled, double-blinded, parallel-group comparative trial. Nishihira J, Nishimura M, Tanaka A, Kagami-Katsuyama H, Yamaguchi A and Taira T. (2018) Functional Foods in Health and Disease, 8(5): 280-291.
  39. モノグルコシルルチン配合緑茶の過剰摂取による非盲検非対照安全性確認試験. 西村三恵, 池田大樹, 堀利行, 橋爪雄志, 中西章仁, 西平　順.(2018) 薬理と治療, 46(6), 1047-1056.
  40. モノグルコシルルチン配合緑茶の12週間継続摂取による脂質代謝に対する有効性および安全性の評価：プラセボ対照ランダム化二重盲検並行群間比較試験. 西村三恵, 池田大樹, 堀利行, 橋爪雄志, 中西章仁, 西平　順. (2018) 薬理と治療, 46(6), 983-996.
  41. Daily Oral Chondroitin Sulfate Oligosaccharides for Knee Joint Pain in Healthy Subjects: A Randomized, Blinded, Placebo-Controlled Study. Nishimura M, Miyamoto N, Nishihira J. (2018) The Open Nutrition Journal, 12, 10-20.
  42. A Randomized, Placebo-Controlled Study on the Safety and Efficacy of Daily Ingestion of Green Tea (Camellia sinensis) cv. “Yabukita” and “Sunrouge” on Eyestrain and Blood Pressure in Healthy Adults. Maeda-Yamamoto M, Nishimura M, Kitaichi N, Nesumi A, Monobe M, Nomura S, Horie Y, Tachibana H, Nishihira J.(2018) Nutrients, 10, 569.
  43. Effect of Lactococcus lactis cremoris YRC3780 on birch pollinosis: a randomized, double-blind, placebo-controlled clinical trial. Uchida K, Motoshima H, Katano N, Hachimura S, Tanaka A, Nishihira J. (2018) Journal of functional foods, 43: 173–179.
  44. タマネギ抽出物の糖代謝改善作用：プラセボ対照二重盲検並行群間比較試験. 佐藤敦哉, 高成凖, 福地有希子, 岡本大作, 田中藍子, 西平順. (2017) 薬理と治療 45(5): 763-771, 2017.
  45. Effects and safety of daily ingestion of plum extract on blood pressure: randomized, double-blinded, placebo-controlled parallel group comparison study. Nishimura M, Kume H, Kadowaki A, Gato N, Nishihira J. (2017) Functional Foods in Health and Disease, 7(11); 873-888.
  46. Double-blind, parallel group, placebo-controlled study of Kjellmaniella crassifolia Miyabe (Gagome) in human: The potential of Gagome to activate the immune system. Nishihira J, Nishimura M, Sugawara M, Kudo M. (2017) Functional Foods in Health and Disease, 7(10):758 -772.
  47. Maitake mushrooms (Grifola frondosa) enhances antibody production in response to influenza vaccination in healthy adult volunteers concurrent with alleviation of common cold symptoms. Nishihira J, Sato M, Tanaka A, Okamatsu M, Azuma T, Tsutsumi N, Yoneyama S. (2017) Functional Foods in Health and Disease, 7(7): 462-482.
  48. A randomized, double-blind, placebo-controlled study to examine the effects of high-isoflavone soybeans “Yukipirika” in climacteric women. Nishimura M, Sugawara M, Kudo M, Nishihira J. (2017) Functional Foods in Health and Disease,7(8):637-660.
  49. A randomized, double-blind, placebo-controlled study evaluating the effects of quercetin-rich onions on cognitive function in elderly subjects. Nishimura M, Ohkawara T, Nakagawa T, Muro T, Sato Y, Satoh H, Kobori M, Nishihira J. （2017）Functional Foods In Health And Disease, 7(6): 353-374.
  50. ヒト介入試験によるそば，大豆，タマネギの機能性の検証 機能性の高い生鮮食品摂取による健康増進の可能性. 西平　順，西村三恵.（2017）化学と生物, 55( 6):421-425.
  51. Lactobacillus gasseri SBT2055 stimulates immunoglobulin production and innate immunity after influenza vaccination in healthy adult volunteers. Nishihira J, Moriya T, Sakai F, Kabuki T, Kawasaki Y, Nishimura M. (2016) Functional Foods in Health and Disease, 6(9): 544-568.
  52. プラセボ対照二重盲検並行群間比較試験によるOligonolの耳鳴り軽減作用の検証.前田　哲宏,　高成 凖, 福地 有希子, 新島 昌裕, 田中 藍子, 西平 順.（2016）薬理と治療, 44(9):1329-1336.
  53. Improvement of triglyceride levels through the intake of enriched-β-conglycinin soybean (Nanahomare) revealed in a randomized, double-blind, placebo-controlled study. Nishimura M, Ohkawara T, Sato Y, Satoh H, Takahashi Y, Hajika M, Nishihira J. (2016) Nutrients, 8(8): 491.
  54. Effectiveness of rutin-rich Tartary buckwheat (Fagopyrum tataricum) ‘Manten-Kirari’ in body weight reduction related to its antioxidant properties: A randomized, double-blind, placebo-controlled study. Nishimura M, Ohkawara T, Sato Y, Satoh H, Ishiguro K, Noda T, Morishita T, Nishihira J. (2016) Journal of Functional Foods, 26:460–469.
  55. Enhancement of the Th1-phenotype immune system by the intake of Oyster mushroom (Tamogitake) extract in a double-blind, placebo-controlled study. Tanaka A, Nishimura M, Sato Y, Sato H, Nishihira J. (2016) Journal of Traditional and Complementary Medicine, 6(4):424–430.
  56. Effects of 4-week continuous ingestion of champignon extract on halitosis and body and fecal odor. Nishihira J, Nishimura M, Tanaka A, Yamaguchi A, Taira T. (2015) Journal of Traditional and Complementary Medicine, 7(1):110-116.
  57. Effects of yogurt containing Lactobacillus plantarum HOKKAIDO on immune function and stress markers. Nishimura M, Ohkawara T, Tetsuka K, Kawasaki Y, Nakagawa R, Satoh H, Sato Y, Nishihira J. (2015) Journal of Traditional and Complementary Medicine, 6(3):275-280.
  58. The effects of herring-roe lyophilized powder on lipid metabolism. Nishimura M, Ohkawara T, Kobayashi H, Sato Y, Munekata M, Nishihira J. (2015) Journal of Traditional and Complementary Medicine, 6(3):247-251.
  59. 北海道産GABA富化米の最適製造条件の設定とヒトへの抗ストレス作用 吉田慎一, 原本正文, 福田朋彦, 水野英則, 田中藍子, 西村三恵, 西平順. 日本食品科学工学会誌, 62(2), 95-103, 2015.
  60. The effects of the extract from roasted chicory (Cichorium intybus) root containing Inulin-type fructans on blood glucose, lipid metabolism and fecal properties. Nishimura M, Ohkawara T, Kanayama T, Kitagawa K, Nishimura H, Nishihira J. (2015) Journal of Traditional and Complementary Medicine, 5(3):161-167.
  61. The effects of white rice containing enriched gamma-amino butyric acid (GABA) on blood pressure. Nishimura M, Yoshida S, Haramoto M, Mizuno H, Fukuda T, Kagami-Katsuyama H, Tanaka A, Ohkawara T, Sato Y and Nishihira J. (2015) Journal of Traditional and Complementary Medicine, 6 (1): 66–71.
  62. Elevation of natural killer cell activity and alleviation of mental stress by the consumption of yogurt containing Lactobacillus gasseri SBT2055 and Bifidobacterium longum SBT2928 in a double-blind, placebo-controlled clinical trial. Nishihira J, Kagami-Katsuyama H, Tanaka A, Nishimura M, Kobayashi T and Kawasaki Y. (2014) Journal of functional foods, 11:261–268.
  63. Effects of dietary fiber with Bacillus coagulans lilac-01 on bowel movement and fecal properties of healthy volunteers with a tendency for constipation. Minamida K, Nishimura M, Miwa K, Nishihira J.(2015) Biosci Biotechnol Biochem, 79(2):300-306.
  64. Effects of enzyme-treated asparagus extract on heat shock protein 70, stress indices, and sleep in healthy adult men. Ito T, Goto K, Takanari J, Miura T, Wakame K, Nishioka H, Tanaka A, Nishihira J.(2014) J Nutr Sci Vitaminol, 60(4):283-290.
  65. Alteration of intestinal flora by the intake of enzymatic degradation products of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) with improvement of skin condition. Nishimura M, Ohkawara T, Kagami-Katsuyama H, Sekiguchi S, Taira T, Tsukada M, Shibata H , Nishihira J. (2013) Journal of functional foods, 7: 487-494.
  66. Pumpkin seed oil extracted from Cucurbita maxima improves urinary disorder in human overactive bladder. Nishimura M, Ohkawara T, Sato H, Takeda H, Nishihira J. (2013) Journal of Traditional and Complementary Medicine, 4(1): 72-74.
  67. Improvement of blood pressure, glucose metabolism, and lipid profile by the intake of powdered asparagus bottom-stems and cladophylls. Nishimura M, Ohkawara T, Kagami-Katsuyama H, Sato H, Nishihira J. (2013) Journal of Traditional and Complementary Medicine, 3(4): 250-255.
  68. Amelioration of abdominal obesity by low-molecular-weight polyphenol (Oligonol) from lyche. Nishihira J, Sato-Ueshima M, Kitadate K, Wakame K, Fujii H. (2009) Journal of functional foods, 1(4): 341-348.

実績紹介・情報発信